Natural Compounds and Their Analogues as Potent Antidotes against the Most Poisonous Bacterial Toxin
نویسندگان
چکیده
منابع مشابه
Berberis vulgaris and its constituent berberine as antidotes and protective agents against natural or chemical toxicities
Berberis vulgaris L (B. vulgaris) and its main constituent berberine have been used in traditional medicine for a long time. This medicinal plant and berberine have many properties that have attracted the attention of researchers over the time. According to several studies, B. vulgaris and berberine exhibited anti-inflammatory, antioxidant, anticonvulsant, antidepressant, anti-Alzheimer, anti-c...
متن کاملIdentification of potent nanobodies to neutralize the most poisonous polypeptide from scorpion venom.
Scorpion venom, containing highly toxic, small polypeptides that diffuse rapidly within the patient, causes serious medical problems. Nanobodies, single-domain antigen-binding fragments derived from dromedary heavy-chain antibodies, have a size that closely matches that of scorpion toxins. Therefore these nanobodies might be developed into potent immunotherapeutics to treat scorpion envenoming....
متن کاملReview of Natural Product-Derived Compounds as Potent Antiglioblastoma Drugs
Common care for glioblastoma multiforme (GBM) is a surgical resection followed by radiotherapy and temozolomide- (TMZ-) based chemotherapy. Unfortunately, these therapies remain inadequate involving severe mortality and recurrence. Recently, new approaches discovering combinations of multiple inhibitors have been proposed along with the identification of key driver mutations that are specific t...
متن کاملBerberis vulgaris and its constituent berberine as antidotes and protective agents against natural or chemical toxicities
Berberis vulgaris L (B. vulgaris) and its main constituent berberine have been used in traditional medicine for a long time. This medicinal plant and berberine have many properties that have attracted the attention of researchers over the time. According to several studies, B. vulgaris and berberine exhibited anti-inflammatory, antioxidant, anticonvulsant, antidepressant, anti-Alzheimer, anti-c...
متن کاملPoisoning - antidotes and their use
J A N UA RY 2 0 0 7 • VO L . 1 4 1 0 • H O S P I TA L P H A R M AC I S T Antidotes play a crucial part in the management of certain poisons, but they are only available for a small number of drugs and chemicals. As pointed out in the previous article (p7), antidotes are only one aspect of the management of a poisoned patient. Until recently, there were no nationally recognised guidelines for em...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Applied and Environmental Microbiology
سال: 2018
ISSN: 0099-2240,1098-5336
DOI: 10.1128/aem.01280-18